RESUMO
El glucagonoma es un raro tumor pancreático que habitualmente se asocia a un síndrome que incluye diabetes, anemia, pérdida de peso y lesiones cutáneas en forma de eritema necrolítico migratorio. Se presenta el caso de una paciente con un glucagonoma maligno tratado con cirugía y octreótida que se manifestó con lesiones cutáneas. Se revisa la fisiopatología, las otras causas de eritema necrolítico, el diagnóstico y diagnóstico diferencial y el tratamiento
Glucagonoma is a rare pancreatic tumor that isusually associated with a syndrome that includes diabetes, anemia, weight loss and skin lesions in the form of necrolyticmigratory erythema. We present the case of a patient with malignant glucagonoma treated with surgery and octreotide, which manifested with skin lesions. The discussion will review the physiopathology, other causes of necrolytic erythema, diagnosis and differential diagnosis and treatment
Assuntos
Feminino , Adulto , Humanos , Glucagonoma/complicações , Glucagonoma/diagnóstico , Glucagonoma/cirurgia , Eritema/complicações , Eritema/diagnóstico , Eritema/terapia , Glucagon/uso terapêutico , Biópsia , Hiperpigmentação/complicações , Eritema/fisiopatologia , Neoplasia Endócrina Múltipla/complicações , Neoplasia Endócrina Múltipla/diagnóstico , Nistatina/uso terapêutico , Queilite/complicações , Queilite/diagnóstico , Glossite/complicações , Glossite/diagnóstico , PrognósticoRESUMO
Glucagonoma is a rare pancreatic tumor that is usually associated with a syndrome that includes diabetes, anemia, weight loss and skin lesions in the form of necrolytic migratory erythema. We present the case of a patient with malignant glucagonoma treated with surgery and octreotide, which manifested with skin lesions. The discussion will review the physiopathology, other causes of necrolytic erythema, diagnosis and differential diagnosis and treatment.
